五味子Schisandra chinensis是木蘭科五味子屬藥用植物，干燥成熟的果實(shí)是其藥用部位。五味子的主要活性成分包括木脂素、多糖、揮發(fā)油等，具有多種藥理作用。系統(tǒng)總結(jié)五味子上市藥品的研究現(xiàn)狀與進(jìn)展，包括五味子藥品的生產(chǎn)工藝、質(zhì)量標(biāo)準(zhǔn)、臨床研究及藥理作用等方面，同時(shí)關(guān)注五味子上市藥品及相關(guān)制品的再開(kāi)發(fā)。現(xiàn)有五味子藥品存在品種單一、臨床定位不清晰、質(zhì)量控制技術(shù)亟待提升等問(wèn)題。未來(lái)需進(jìn)一步明確其臨床應(yīng)用定位，優(yōu)化質(zhì)量標(biāo)準(zhǔn)和控制技術(shù)，推動(dòng)其國(guó)際化發(fā)展，從而提升五味子藥品的臨床價(jià)值與市場(chǎng)競(jìng)爭(zhēng)力。

Schisandra chinensis (Turcz.) Baill. is a kind of medicinal plant, which belongs to the family of Magnoliaceae, Schisandra. Its medicinal part is the dried ripe fruits. The main bioactive components of S. chinensis, including lignans, polysaccharides, and volatile oils, exhibit various pharmacological effects. This review systematically summarized the current state and research progress of commercial pharmaceutical products of S. chinensis. The production processes, quality standards, clinical research and related pharmacological effects of these products were analyzed. We also focused on the redevelopment of these commercial products and related products. The existing drugs face issues such as limited variety, unclear clinical orientation, and the need for improvements in quality control techniques. In the further, it is necessary to clarify the clinical application orientation, optimize quality standards and control techniques, and promote international development to enhance the clinical value and market competitiveness of S. chinensis products.

R282.71

廣州市科技計(jì)劃項(xiàng)目基礎(chǔ)與應(yīng)用基礎(chǔ)研究專題（2023A04J1101）;國(guó)家自然科學(xué)基金青年基金（82104095）;廣東省科技廳與澳門科學(xué)技術(shù)發(fā)展基金聯(lián)合科研資助項(xiàng)目（0012/2022/AGJ）