白芍Paeoniae Radix Alba為臨床常用的中藥，主治胸腹脅肋疼痛、瀉痢腹痛、自汗盜汗、陰虛發(fā)熱、月經(jīng)不調(diào)、崩漏等。其功效與其活性成分密切相關(guān)，現(xiàn)代藥理研究表明，白芍有保肝、抗肝纖維化、鎮(zhèn)痛、抗抑郁、降血糖、心血管保護、抗氧化、調(diào)節(jié)免疫及抗腫瘤等作用。目前研究發(fā)現(xiàn)，產(chǎn)地、種質(zhì)、栽培措施、采收加工、炮制方法等因素均會導致活性成分含量差異，并影響其藥理作用。通過查閱歷代本草、醫(yī)藥典籍及國內(nèi)外相關(guān)文獻，從白芍的活性成分、藥理作用及影響活性成分表達的因素進行論述，為白芍今后研究、臨床應用及相關(guān)藥品的開發(fā)提供理論參考。

Baishao (Paeoniae Radix Alba) is a commonly used traditional Chinese medicine in clinical practice. It mainly treats chest, abdominal pain, diarrhea and abdominal pain, spontaneous sweating, night sweats, yin deficiency fever, irregular menstruation, metrorrhagia, etc. Its efficacy is closely related to its active ingredients. Modern pharmacological studies have shown that Paeoniae Radix Alba has liver protection, anti-liver fibrosis, analgesia, antidepressant, blood sugar lowering, cardiovascular protection, antioxidant, immune regulation and anti-tumor effects. Current research has found that factors such as origin, germplasm, cultivation measures, harvesting processing, processing methods, storage, compatibility and decocting methods will all lead to differences in the content of active ingredients and affect the pharmacological effects. The active ingredients, pharmacological effects and the influence of various factors on its active ingredients of Paeoniae Radix Alba by reviewing the herbal medicines, medical classics and relevant literature at home and abroad, to provide theoretical reference for future research, clinical application and development of related pharmaceuticals Paeoniae Radix Alba.

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國家自然科學基金面上項目（81573870）;國家中醫(yī)藥管理局第五批全國中醫(yī)臨床優(yōu)秀人才研修項目（國中醫(yī)藥人教函[2022]239號）;國家中醫(yī)藥管理局第五批全國中醫(yī)臨床優(yōu)秀人才研修項目（國中醫(yī)藥人教函[2022]1號）