隨著消費者對健康食品的需求增加，藥食同源中藥材因其獨特的藥用和食用價值而日益受到關(guān)注。然而，農(nóng)藥殘留問題嚴(yán)重影響了藥食同源中藥材的質(zhì)量和安全性。質(zhì)譜技術(shù)作為一種高靈敏度、高選擇性的分析技術(shù)，能夠準(zhǔn)確、快速地檢測和定量分析復(fù)雜樣品中的農(nóng)藥殘留，因此在藥食同源中藥材的質(zhì)量控制和安全性評估中具有重要的應(yīng)用前景。通過簡述質(zhì)譜技術(shù)的組成及其發(fā)展歷程，重點綜述了常用質(zhì)譜技術(shù)在藥食同源中藥材農(nóng)藥殘留檢測中的應(yīng)用，展望了小型化、綠色化、智能化、高靈敏的發(fā)展趨勢，為藥食同源中藥材的質(zhì)量安全提供保障。

The increasing demand for healthful foods has heightened interest in Chinese medicinal materials due to their unique medicinal and edible properties, particularly those with the homology of medicine and food. However, concerns regarding pesticide residue contamination have raised significant issues concerning the quality and safety of these medicinal materials Consequently, mass spectrometry (MS), a highly sensitive and selective analytical technology, offers considerable potential for the accurate and rapid detection and quantitative analysis of pesticides in complex samples. This makes it an invaluable tool for the quality control and safety assessment of Chinese medicinal materials with the homology of medicine and food. This review will briefly outline the components of mass spectrometry and its developmental history, with a focus on the application of commonly used mass spectrometry techniques in detecting pesticide residues in Chinese medicinal materials with homology of medicine and food. Additionally, the review will explore future trends in the miniaturization, greening, intelligence, and enhanced sensitivity of mass spectrometry technologies, which hold the potential to further ensure the quality and safety of these medicinal materials.

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生物醫(yī)藥與健康重點領(lǐng)域?qū)ｍ棧ɑ浗炭坪?[2021] 8號）；廣東省教育廳重點項目（2021ZDZX2060）；2022年佛山市南海區(qū)重點領(lǐng)域科技攻關(guān)專項（南科 [2023] 20號-18）