目的 對2011—2025年新興熱門領(lǐng)域AI＋中藥活性多糖的發(fā)展趨勢和研究熱點(diǎn)進(jìn)行知識圖譜分析，為該領(lǐng)域的進(jìn)一步發(fā)展提供實(shí)用性參考。方法 全面檢索Web of Science（WOS）中的相關(guān)英文文獻(xiàn)，使用VOSviewer和CiteSpace 2種重要文獻(xiàn)計(jì)量學(xué)工具進(jìn)行可視化分析，包括發(fā)文趨勢、國家和期刊分布、作者與機(jī)構(gòu)合作網(wǎng)絡(luò)分析，關(guān)鍵詞共現(xiàn)、聚類、時間線和突現(xiàn)分析以及高被引文獻(xiàn)分析。結(jié)果 最終得到AI＋中藥活性多糖研究領(lǐng)域高質(zhì)量文獻(xiàn)116篇，發(fā)文趨勢呈現(xiàn)新興學(xué)科演進(jìn)特征，中國和美國是發(fā)文量最多的國家，International Journal of Biological Macromolecules是發(fā)表論文最多的期刊，中國科學(xué)院為核心機(jī)構(gòu)。研究熱點(diǎn)涵蓋智能算法驅(qū)動的中藥活性多糖提取、分離、鑒定及活性預(yù)測，多糖基生物材料的智能化開發(fā)，以及精準(zhǔn)醫(yī)療與癌癥疾病預(yù)防調(diào)控等方向。結(jié)論 AI＋中藥活性多糖當(dāng)前研究熱點(diǎn)具有極大研究前景，研究領(lǐng)域展現(xiàn)高速發(fā)展態(tài)勢，有可能成為未來重要的研究方向。

Objective To analyze the knowledge mapping of the development trend and research hotspots in the emerging hot field of AI + active polysaccharides in traditional Chinese medicine from 2011 to 2025, so as to provide a practical reference for the further development of this field. Methods A comprehensive search of relevant English literature in Web of Science (WOS) was conducted, and 2 important bibliometric tools, VOSviewer and CiteSpace, were used to perform visual analysis, including the trend of publications, distribution of countries and journals, network analysis of authors’ and institutions’ cooperation, keyword co-occurrence, clustering, timeline and emergence analyses as well as the analysis of highly cited literature. Results Finally, a total of 116 high-quality literatures were obtained in the research field of AI + active polysaccharides in traditional Chinese medicine, and the trend of publication showed the characteristics of emerging disciplinary evolution, with China and the United States being the countries with the largest number of publications, International Journal of Biological Macromolecules being the journal with the largest number of publications, and Chinese Academy of Sciences being the core institution. The research hotspots cover intelligent algorithm-driven polysaccharide extraction, isolation, characterization and activity prediction, intelligent development of polysaccharide-based biomaterials, and precision medicine and cancer prevention and regulation. Conclusion The current research hotspots of AI + active polysaccharides in traditional Chinese medicine have great research prospects, and the research field shows a rapid development trend, which may become an important research direction in the future.

G350;R285

國家自然科學(xué)基金資助項(xiàng)目（U2202213）；國家自然科學(xué)基金資助項(xiàng)目（82374098）