[關(guān)鍵詞]
[摘要]
歷代醫(yī)家對當歸Angelicae Sinensis Radix藥性的描述為甘、辛、苦、溫；入肝、心、脾經(jīng)，能升能降。隨著中醫(yī)藥的發(fā)展和醫(yī)藥學家的不斷實踐，形成了多種各具特色與優(yōu)勢的當歸炮制飲片，研究表明不同的炮制技術(shù)會改變其藥性，從而在臨床應用上有特定的優(yōu)勢。通過系統(tǒng)梳理當歸各炮制品的分類、歷代炮制方法及現(xiàn)代使用情況，并基于中藥藥性理論從物質(zhì)基礎(chǔ)、藥理學和代謝組學層面闡明不同炮制品的藥性變化和臨床應用甄別，為當歸炮制方法的傳承、臨床實踐提供理論依據(jù)，同時為未來研究方向提出建議，推動其在中藥炮制中更廣泛的應用。
[Key word]
[Abstract]
The medicinal properties of Danggui (Angelicae Sinensis Radix) were described as sweet, pungent, bitter and warm. It enters the liver, heart and spleen meridians and can ascend and descend. With the development of traditional Chinese medicine and the continuous practice of medical scholars, a variety of processed Angelicae Sinensis Radix decoction pieces with distinct characteristics and advantages have been formed. Studies have shown that different processing techniques can alter its medicinal properties, thereby endowing it with specific advantages in clinical application. In this paper, the classification, processing methods and modern use of Angelicae Sinensis Radix products were systematically reviewed. Based on the theory of traditional Chinese medicine properties, the changes of medicinal properties of different Angelicae Sinensis Radix products and the screening of clinical applications were expounded from the aspects of material basis, pharmacology and metabolomics, aiming to provide theoretical basis for the inheritance of Angelicae Sinensis Radix processing methods and clinical practice, and at the same time, suggestions for future research directions were put forward. Promoting its wider application in processing of traditional Chinese medicine.
[中圖分類號]
R28
[基金項目]
國家重點研發(fā)計劃“中醫(yī)藥現(xiàn)代化研究”重點專項（2023YFC3504205）；特色炮制技術(shù)規(guī)律發(fā)掘——麩制（GZY-KJS-2022-051）；中藥炮制技術(shù)傳承創(chuàng)新團隊（CXTD22003）；中藥炮制（炆法）等關(guān)鍵技術(shù)重點研究室（贛中醫(yī)藥科教字 [2022] 8號）；江西省“雙千人才”計劃項目 [贛才辦字（2019）9號]；江西省中醫(yī)藥產(chǎn)業(yè)科技創(chuàng)新聯(lián)合體產(chǎn)業(yè)鏈協(xié)同攻關(guān)項目（20224BBG72001）；江西省自然科學基金項目（20224ACB206048）；國家自然科學基金資助項目（82360771）；中藥炮制傳承創(chuàng)新與轉(zhuǎn)化江西省重點實驗室（2024SSY07091）；江西省標準創(chuàng)新基地（醫(yī)藥）；國家重點研發(fā)計劃“中醫(yī)藥現(xiàn)代化研究”重點專項（2024YFC3507005）；江西中醫(yī)藥大學研究生創(chuàng)新專項（XJ-S202481）
